Roxitin TABLETS

ROXITINE Tablets
Paroxetine

Therapeutic Segment:
Psychiatry
General Practitioners

Description

ROXITINE Tablets contain Paroxetine, a selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression and various anxiety disorders. It helps improve mood, reduce anxiety, and restore emotional balance by increasing serotonin levels in the brain.

ROXITINE Tablets Specification

Requires Prescription: YES

How It Works

Paroxetine works by selectively inhibiting the reuptake of serotonin (5-HT) in the central nervous system. This increases serotonin availability in the synaptic cleft, enhancing mood and reducing symptoms of depression and anxiety disorders.

Usage and Safety

Side Effects
Common: Nausea, drowsiness, dizziness, insomnia, dry mouth, sweating, sexual dysfunction.

Less Common: Anxiety, agitation, tremors, blurred vision, constipation, vomiting, weight changes, decreased appetite.

Drug Interactions
May interact with: monoamine oxidase inhibitors (MAOIs), other SSRIs, SNRIs, tricyclic antidepressants, lithium, tramadol, triptans, anticoagulants (e.g., warfarin), NSAIDs, linezolid, and CYP2D6 inhibitors.

Indications

Paroxetine is indicated for:

• Major depressive disorder (MDD)

• Generalized anxiety disorder (GAD)

• Panic disorder

• Social anxiety disorder

• Obsessive-compulsive disorder (OCD)

• Post-traumatic stress disorder (PTSD)

Contraindications (When Not to Use)

• Known hypersensitivity to Paroxetine

• Concurrent use with MAO inhibitors or within 14 days of discontinuation

• Use with thioridazine or pimozide

Precautions

Use with caution in patients with a history of seizures, bipolar disorder, liver or kidney impairment, or those at risk of bleeding. Dose adjustment may be required in elderly patients.

Warnings

Warning 1:
Antidepressants may increase the risk of suicidal thoughts and behaviors in young adults, especially during initial treatment or dose adjustments.

Warning 2:
Risk of serotonin syndrome when used with other serotonergic drugs; immediate medical attention is required if symptoms occur.

Warning 3:
Abrupt discontinuation may lead to withdrawal symptoms; tapering of dose is recommended.

Additional Information

Pregnancy Category:
Use during pregnancy only if clearly needed and under medical supervision.

Storage:
Store at room temperature, away from direct light and heat.