DIRE OD Capsules
DIRE OD Capsules
Quatrefolic (L-Methylfolate) + DHA (Docosahexaenoic Acid)
Therapeutic Segment:
Gynecology
General Practitioners
Description
DIRE OD Capsules combine Quatrefolic (L-Methylfolate), the active form of folic acid, with DHA, an essential omega-3 fatty acid. This formulation is designed to support maternal health, fetal development, and overall nutritional balance. It plays a crucial role in neural tube development, brain function, and red blood cell formation.
DIRE OD Capsules Specification
Requires Prescription: NO
How It Works
L-Methylfolate is the biologically active form of folate that is readily utilized by the body, supporting DNA synthesis and cell division. DHA is a key structural component of the brain and retina, contributing to neurological and visual development. Together, they support healthy pregnancy outcomes and enhance maternal and fetal well-being.
Usage and Safety
Side Effects
Common: Nausea, mild gastrointestinal discomfort, bloating.
Less Common: Headache, dizziness, allergic reactions, fishy aftertaste (due to DHA).
Drug Interactions
May interact with: antiepileptic drugs (e.g., phenytoin), methotrexate, sulfasalazine, oral contraceptives, and anticoagulants.
Indications
This combination is indicated for:
Nutritional support during pregnancy and lactation
Prevention of neural tube defects
Folate deficiency
Support of fetal brain and eye development
General women’s health and preconception care
Contraindications (When Not to Use)
Known hypersensitivity to folate, DHA, or any component of the formulation
Precautions
Use with caution in patients with vitamin B12 deficiency, as folate supplementation may mask its symptoms. Patients on anticoagulant therapy should consult a physician before use.
Warnings
Warning 1:
Should not be used as a substitute for a balanced diet during pregnancy.
Warning 2:
Excessive intake should be avoided unless prescribed by a healthcare professional.
Warning 3:
Consult a physician before use in patients with underlying medical conditions.
Additional Information
Pregnancy Category:
Recommended under medical supervision during pregnancy and lactation.
Storage:
Store at room temperature, away from direct light and heat.